Developments in Determining Manageability of Prostate Cancer


Prostate Cancer pic
Prostate Cancer

At Metro Chicago Surgical Oncology LLC, Dr. Alan Sadah provides urological care spanning a variety of procedures, including ultrasound and biopsies. Dr. Alan Sadah has extensive experience treating tumors, including through his work on staff at the Chicago Prostate Cancer Center.

Recent research at the University of York suggests new avenues for distinguishing manageable cancer from prostate cancer that requires surgery. For those with non-life-threatening forms of prostate disease, active monitoring can prove less expensive and result in a significantly lower number of negative side effects.

The research, which focuses on cancer type alterations, involves the comparison of hundreds of noncancerous tissue samples with cancerous samples. The scientists algorithmically eliminated genetic pattern noise among nearly a million markers, which left them with 17 distinct genetic markers associated with prostate cancer. This knowledge has the potential to result in fewer unnecessary surgeries and radiotherapy treatments, lessening the financial burden associated with prostate cancer surgery and making medical treatment more effective.

The Prostate Gland – Its Function in the Male Body


Metro Chicago Surgical Oncology, Dr. Alan Sadah pic
Metro Chicago Surgical Oncology, Dr. Alan Sadah

Since 2011, Dr. Alan Sadah has served as a urologist at Metro Chicago Surgical Oncology. Dr. Alan Sadah has practiced in his specialty for more than 25 years, during which time he has served numerous patients with prostate cancer and spoken extensively on the topic.

The prostate gland is a component of the male reproductive system. It produces and secretes prostate fluid, which serves as a carrier for semen during the ejaculation process.

When a man ejaculates, sperm travel from the testes through the vas deferens. These tubes carry the semen into the region of the prostate, which circumscribes the urethra underneath the bladder. The prostate then contracts, separating the bladder from the prostate, and releases fluid and semen into the urethra.

Older men are at increased risk of benign prostate hyperplasia (BPH), an enlargement of the prostate that causes a compression of the urethra and irritation of the bladder. This affects more than 60 percent of men in their 60s and 90 percent of men in their 70s and 80s.

Symptoms of BPH include a weak or interrupted urine stream, urinary leakage, or frequent urination. These symptoms of prostate growth may also indicate prostate cancer, which affected 200,000 men at the time the National Cancer Institute collected data in 2010.

Urinary Incontinence Risk Higher among Overweight and Obese Women


Urinary Incontinence pic
Urinary Incontinence

A board-certified surgeon and urologist, Dr. Alan Sadah practices with Metro Chicago Surgical Oncology. Also on staff at Advocate Good Samaritan Hospital, Alexian Brothers Medical Center, Chicago Prostate Cancer Center, Gottlieb Memorial Hospital, Kindred Hospital, St. Alexius Medical Center, Westlake Hospital, and West Suburban Medical Center, Dr. Alan Sadah lectures and writes publications on numerous subjects, including incontinence.

Recently, a review of 14 previously published studies revealed that women who are overweight or obese have a greater risk of developing urinary incontinence. The review, performed by scientists at the University of Queensland, looked at more than 47,000 women in eight countries. The women had various subtypes of urinary incontinence, including urge, stress, mixed, and severe.

According to the results, the risk of urinary incontinence increased by a third in women who were overweight. As weight increased, the risk of incontinence also increased.

Among women who were obese, the risk of developing incontinence was two times higher than the risk of women with a “normal” body mass index. Weight was the only significant difference that researchers found.

Comparisons between women under the age of 35 and women between the ages of 36 and 55 showed no significant difference in risk of urinary incontinence. Further, researchers found no difference in risk for the different subtypes of urinary incontinence.